Studies examining fibroblast and endothelial cell systems show increased phosphorylation of focal adhesion kinase and paxillin, two proteins central to cytoskeletal organization and cell adhesion signaling
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There are additional scoring assessments that are available, such as time to partial re-epithelialization, time to complete re-epithelialization, and BSA involved, among others
Kojima ML, de Rooij DG, Page DC (2019) Amplification of a broad transcriptional program by a common factor triggers the meiotic cell cycle in mice
It most commonly begins in middle age, often between 30 and 60 years old
Most patients can begin immediately after evaluation
